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1

Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase

McCorvie, Thomas J., Kopec, Jolanta, Pey, Angel L., Fitzpatrick, Fiona, Patel, Dipali, Chalk, Rod, Shrestha, Leela, Yue, Wyatt W.

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 1.94 MB

english, 2016

2

The lower limits for protein stability and foldability in primary hyperoxaluria type I

Mesa-Torres, Noel, Salido, Eduardo, Pey, Angel L.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

3

Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency

Pey, Angel L., Mesa-Torres, Noel, Chiarelli, Laurent R., Valentini, Giovanna

Journal:

Year:

2013

Language:

english

File:

PDF, 2.23 MB

english, 2013

4

NAD(P)H quinone oxidoreductase 1 (NQO1): an enzyme which needs just enough mobility, in just the right places

Pey, Angel L., Megarity, Clare F, Timson, David J

Journal:

Bioscience Reports

Year:

2018

Language:

english

File:

PDF, 757 KB

english, 2018

5

pH-dependent relationship between thermodynamic and kinetic stability in the denaturation of human phosphoglycerate kinase 1

Journal:

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

6

Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine

Calvo, Ana C., Pey, Angel L., Miranda-Vizuete, Antonio, Døskeland, Anne P., Martinez, Aurora

Journal:

Biochemical Journal

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

7

Tetrahydrobiopterin for patients with phenylketonuria

Angel L Pey, Aurora Martinez

Journal:

Year:

2007

Language:

english

File:

PDF, 200 KB

english, 2007

8

Erratum: Erratum: Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

Medina-Carmona, Encarnación, Palomino-Morales, Rogelio J., Fuchs, Julian E., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Salido, Eduardo, Timson, David J., Pey, Angel L.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 117 KB

english, 2016

9

Improving the activity and stability of human galactokinase for therapeutic and biotechnological applications

McAuley, Margaret, Mesa-Torres, Noel, McFall, Aisling, Morris, Sarah, Huang, Meilan, Pey, Angel, Timson, David J

Journal:

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

10

Correction to Conformational Properties of Nine Purified Cystathionine β-Synthase Mutants

Hnı́zda, Aleš, Majtan, Tomas, Liu, Lu, Pey, Angel L., Carpenter, John F., Kodı́ček, Milan, Kožich, Viktor, Kraus, Jan P.

Journal:

Year:

2012

Language:

english

File:

PDF, 136 KB

english, 2012

11

Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2

Ana C. Calvo, Tanja Scherer, Angel L. Pey, Ming Ying, Ingeborg Winge, Jeffrey McKinney, Jan Haavik, Beat Thöny, Aurora Martinez

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 445 KB

english, 2010

12

The interplay between protein stability and dynamics in conformational diseases: The case of hPGK1 deficiency

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

13

A mechanism for cancer-associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R

Muñoz, Inés G., Morel, Bertrand, Medina-Carmona, Encarnación, Pey, Angel L.

Journal:

Year:

2017

Language:

english

File:

PDF, 582 KB

english, 2017

14

Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site

Rizzuti, Bruno, Bartucci, Rosa, Pey, Angel L., Guzzi, Rita

Journal:

Archives of Biochemistry and Biophysics

Year:

2019

Language:

english

File:

PDF, 2.04 MB

english, 2019

15

Superstoichiometric binding ofL-Phe to phenylalanine hydroxylase fromCaenorhabditis elegans: evolutionary implications

Marte I. Flydal, Tonje C. Mohn, Angel L. Pey, Jessica Siltberg-Liberles, Knut Teigen, Aurora Martinez

Journal:

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

16

Phenylalanine hydroxylase expression in primary rat hepatocytes is modulated by oxygen concentration

Ming Ying, Angel L. Pey, Niels Aarsæther, Aurora Martinez

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

17

The activity of wild-type and mutant phenylalanine hydroxylase and its regulation by phenylalanine and tetrahydrobiopterin at physiological and pathological concentrations: An isothermal titration calorimetry study

Angel L. Pey, Aurora Martinez

Journal:

Molecular Genetics and Metabolism

Year:

2005

Language:

english

File:

PDF, 378 KB

english, 2005

18

Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site

Rizzuti, Bruno, Bartucci, Rosa, Pey, Angel L., Guzzi, Rita

Journal:

Archives of Biochemistry and Biophysics

Year:

2019

File:

PDF, 2.04 MB

2019

19

Hernia ureteroinguinal

Pareja-López, Ángel, Sevilla-Cecilia, Carlota, Pey-Camps, Albert, Dominguez-Tristancho, José Luis, Muteb, Murad

Journal:

Cirugía Española

Year:

2013

File:

PDF, 589 KB

2013

20

BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells

Georg, Ina, Díaz-Barreiro, Alejandro, Morell, Maria, Pey, Angel L., Alarcón-Riquelme, Marta E.

Journal:

Cellular & Molecular Immunology

Year:

2019

Language:

english

File:

PDF, 3.39 MB

english, 2019

21

Do elementary flux modes combine linearly at the “atomic” level? Integrating tracer-based metabolomics data and elementary flux modes

Jon Pey, Constantinos Theodoropoulos, Alberto Rezola, Angel Rubio, Marta Cascante, Francisco J. Planes

Journal:

Year:

2011

Language:

english

File:

PDF, 707 KB

english, 2011

22

Conformational Properties of Nine Purified Cystathionine β-Synthase Mutants

Hnízda, Aleš, Majtan, Tomas, Liu, Lu, Pey, Angel L., Carpenter, John F., Kodíček, Milan, Kožich, Viktor, Kraus, Jan P.

Journal:

Year:

2012

Language:

english

File:

PDF, 424 KB

english, 2012

23

Lesión diafiso-metafisaria distal femoral izquierda en paciente de 13 años

Delgado García, M., Mitjavila Casanovas, M., de los Ángeles Balsa Bretón, M.a, Castillejos Rodríguez, L., Alonso García, P., Cañamaque García, L., Penín González, J., Pey Illera, C.

Journal:

Revista Española de Medicina Nuclear

Year:

2000

File:

PDF, 96 KB

2000

24

FAD binding overcomes defects in activity and stability displayed by cancer-associated variants of human NQO1

Pey, Angel L., Megarity, Clare F., Timson, David J.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 3.28 MB

english, 2014

25

The Development of Laparoscopic Surgery in Spain

Feliu, Xavier, Targarona, Eduardo Mar&iacute, a, Garc&iacute, a-Agust&iacute, , Ana, Pey, Albert, Carrillo, Angel, Lacy, Antonio Mar&iacute, a, Morales, Salvador, Salvador, Jos&eacute, Luis, Torres, Anton

Journal:

Digestive Surgery

Year:

2004

Language:

english

File:

PDF, 97 KB

english, 2004

26

Systemic Alanine Glyoxylate Aminotransferase Messenger RNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1

Kukreja, Anjli, Lasaro, Melissa, Cobaugh, Christian, Forbes, Chris, Tang, Jian-Ping, Gao, Xiang, Martin-Higueras, Cristina, Pey, Angel L., Salido, Eduardo, Sobolov, Susan, Subramanian, Romesh R.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2019

File:

PDF, 822 KB

2019

27

The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein

Pey, Angel L., Majtan, Tomas, Kraus, Jan P.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

28

Human cystathionine β-synthase (CBS) contains two classes of binding sites for S -adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM

Pey, Angel L., Majtan, Tomas, Sanchez‑Ruiz, Jose M., Kraus, Jan P.

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

29

In-Silico Prediction of Key Metabolic Differences between Two Non-Small Cell Lung Cancer Subtypes

Rezola, Alberto, Pey, Jon, Rubio, Ángel, Planes, Francisco J., Singh, Pankaj K.

Journal:

Year:

2014

Language:

english

File:

PDF, 640 KB

english, 2014

30

La cirugía laparoscópica en España. Resultados de la encuesta nacional de la Sección de Cirugía Endoscópica de la Asociación Española de Cirujanos

Feliu, Xavier, Targarona, Eduardo M., García, Ana, Pey, Albert, Carrillo, Angel, María Lacy, Antonio, Morales-Conde, Salvador, Luis Salvador, Jose, Torres, Antonio, Veloso, Enrique

Journal:

Cirugía Española

Year:

2003

File:

PDF, 85 KB

2003

31

Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability

Medina-Carmona, Encarnación, Rizzuti, Bruno, Martín-Escolano, Rubén, Pacheco-García, Juan Luis, Mesa-Torres, Noel, Neira, José L., Guzzi, Rita, Pey, Angel L.

Journal:

International Journal of Biological Macromolecules

Year:

2018

Language:

english

File:

PDF, 1.65 MB

english, 2018

32

[ACM Press the 8th international conference - Manchester, England (1994.07.11-1994.07.15)] Proceedings of the 8th international conference on Supercomputing - ICS '94 - A generalized vision of some parallel bidiagonal systems solvers

Larriba-Pey, Josep-L., Navarro, Juan J., Roig, Oriol, Jorba, Angel

Year:

1994

Language:

english

File:

PDF, 899 KB

english, 1994

33

Should we consider IgG hypogammaglobulinemia a risk factor for severe complications of Ludwig angina?

Baez-Pravia, Orville V., Díaz-Cámara, Miriam, De La, Oscar, Pey, Carlos, Ontañón Martín, Mercedes, Jimenez Hiscock, Luis, Morató Bellido, Begoña, Córdoba Sánchez, Ángel Luis

Journal:

Medicine (Medicine Publishing Company Ltd)

Year:

2017

Language:

english

File:

PDF, 489 KB

english, 2017

34

Engineering proteins with tunable thermodynamic and kinetic stabilities

Angel L. Pey, David Rodriguez-Larrea, Susanne Bomke, Susanne Dammers, Raquel Godoy-Ruiz, Maria M. Garcia-Mira, Jose M. Sanchez-Ruiz

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

35

[ACM Press the 16th International Database Engineering & Applications Sysmposium - Prague, Czech Republic (2012.08.08-2012.08.10)] Proceedings of the 16th International Database Engineering & Applications Sysmposium on - IDEAS '12 - Efficient graph management based on bitmap indices

Martínez-Bazan, Norbert, Águila-Lorente, M. Ángel, Muntés-Mulero, Victor, Dominguez-Sal, David, Gómez-Villamor, Sergio, Larriba-Pey, Josep-L.

Year:

2012

Language:

english

File:

PDF, 882 KB

english, 2012

36

The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine–glyoxylate aminotransferase

Mesa‑Torres, Noel, Yunta, Cristina, Fabelo‑Rosa, Israel, Gonzalez‑Rubio, Juana María, Sánchez‑Ruiz, José M., Salido, Eduardo, Albert, Armando, Pey, Angel L.

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 2.19 MB

english, 2014

37

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2

Giménez-Mascarell, Paula, Oyenarte, Iker, Hardy, Serge, Breiderhoff, Tilman, Stuiver, Marchel, Kostantin, Elie, Diercks, Tammo, Pey, Angel L., Ereño-Orbea, June, Martínez-Chantar, María Luz, Khalaf-Na

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

38

Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism

Medina-Carmona, Encarnación, Neira, Jose L., Salido, Eduardo, Fuchs, Julian E., Palomino-Morales, Rogelio, Timson, David J., Pey, Angel L.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.58 MB

english, 2017

39

Protein Homeostasis Diseases || Protein homeostasis and disease

Year:

2020

File:

PDF, 727 KB

2020

40

Protein Stability, Folding and Misfolding in Human PGK1 Deficiency

Valentini, Giovanna, Maggi, Maristella, Pey, Angel

Journal:

Year:

2013

Language:

english

File:

PDF, 805 KB

english, 2013

41

Insights into human phosphoglycerate kinase 1 deficiency as a conformational disease from biochemical, biophysical, and in vitro expression analyses

Pey, Angel L., Maggi, Maristella, Valentini, Giovanna

Journal:

Journal of Inherited Metabolic Disease

Year:

2014

Language:

english

File:

PDF, 870 KB

english, 2014

42

The metastability of human UDP-galactose 4′-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding

Pey, Angel L., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Timson, David J.

Journal:

Archives of Biochemistry and Biophysics

Year:

2014

Language:

english

File:

PDF, 3.57 MB

english, 2014

43

Molecular Recognition of PTS-1 Cargo Proteins by Pex5p: Implications for Protein Mistargeting in Primary Hyperoxaluria

Mesa-Torres, Noel, Tomic, Nenad, Albert, Armando, Salido, Eduardo, Pey, Angel

Journal:

Year:

2015

Language:

english

File:

PDF, 39.48 MB

english, 2015

44

Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria

Majtan, Tomas, Pey, Angel L., Kraus, Jan P.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.44 MB

english, 2016

45

The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity

Anoz-Carbonell, Ernesto, Timson, David J., Pey, Angel L., Medina, Milagros

Journal:

Year:

2020

File:

PDF, 4.39 MB

2020

46

Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein

Pacheco-GarcÃa, Juan Luis, Cano-MuÃ±oz, Mario, SÃ¡nchez-Ramos, Isabel, Salido, Eduardo, Pey, Angel L.

Journal:

Journal of Personalized Medicine

Year:

2020

File:

PDF, 4.90 MB

2020

47

[IEEE 2011 IEEE Statistical Signal Processing Workshop (SSP) - Nice, France (2011.06.28-2011.06.30)] 2011 IEEE Statistical Signal Processing Workshop (SSP) - Exploring the connectivity structure in metabolic networks: Going beyond graphs via discrete optimization

Pey, Jon, Rubio, Angel, Crespo, Pedro, Planes, Francisco J., Beasley, John E.

Year:

2011

Language:

english

File:

PDF, 1.61 MB

english, 2011

48

Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution

Medina-Carmona, Encarnación, Fuchs, Julian E., Gavira, Jose A., Mesa-Torres, Noel, Neira, Jose L., Salido, Eduardo, Palomino-Morales, Rogelio, Burgos, Miguel, Timson, David J., Pey, Angel L.

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 1.39 MB

english, 2017

49

Towards Accurate GenotypeâPhenotype Correlations in the CYP2D6 Gene

Journal:

Journal of Personalized Medicine

Year:

2020

File:

PDF, 191 KB

2020

50

Primary hyperoxalurias: Disorders of glyoxylate detoxification

Eduardo Salido, Angel L. Pey, Rosa Rodriguez, Victor Lorenzo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

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